Marcus P. Zillman, M.S., A.M.H.A. Author/Speaker/Consultant

<$BlogRSDUrl$> Marcus P. Zillman, M.S., A.M.H.A. Author/Speaker/Consultant

Marcus P. Zillman, M.S., A.M.H.A. Author/Speaker/Consultant
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Friday, May 19, 2006

Translational OncoGenomics

Translational OncoGenomics
http://www.la-press.com/tog.htm

The primary mission of Translational OncoGenomics is to provide an open-access, peer-reviewed, rapid-publication forum to assist in the dissemination of novel genetic, epigenetic and molecular pathway information related to clinical cancer. The journal is designed to meet the scientific and public need for such a forum in order to process the accelerating acquisition of genomic data resultant from recent technological advances in and international programmatic commitments to this area of research. Particularly encouraged is the submission of papers with a translational connection to human cancer from basic science to ethical considerations related to the application of oncogenomic discoveries for diagnostic and prognostic purposes in clinical trials and for anti-cancer drug development. An important objective will be to contribute information published in this forum to comprehensive nternationally-accessible genomic databases in order to foster the identification of molecular targets for the therapy of specific cancers. The following topics of interest are structured on the premise that cancer is a highly heterogeneous disease involving elements in the host as well as in the tumor itself:

* Constitutional cancer susceptibility factors
* Polymorphic variants and linkage disequilibrium related to cancer risk
* Somatic genetic and epigenetic events related to cancer initiation
* Precancerous genetic and epigenetic alterations
* Somatic genetic and epigenetic events related to cancer progression
* Genetic and epigenetic events related to metastases
* Genetic and epigenetic events related to tumor/normal cell/tissue interactions
* Mutation identification in cancer
* Gene copy number abnormalities in cancer
* Gene rearrangements in cancer
* Oncogene and suppressor gene discovery and characterization
* MicroRNAs in cancer
* Molecular pathway alterations related to genetic or epigenetic alterations
* Genomic methylation effects on gene transcription profiles
* Gene expression profiles related to cancer classification and progression
* Gene transcript splicing variations related to cancer
* Constitutional variations affecting anti-cancer drug efficacy and toxicity
* Genetic or epigenetic alterations related to drug sensitivity or resistance
* Gene expression profiles related to drug sensitivity or resistance
* Genomic stratification and monitoring applications in clinical trials
* Integration of genomic and clinical database information
* Technological advances in genomics
* Quality control and ethical issues related to applied oncogenomics

Translational OncoGenomics will publish: Original Research papers; Short Communications; Application Notes; Reviews; and Letters. This has been added to Biological Informatics Subject Tracer™ Information Blog.

posted by Marcus Zillman | 4:09 AM

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